The COVID-Miner is a bioinformatics framework that enables to the extraction of single mutations, Pangolin lineages, and consensus from GISAID SARS-CoV-2 sequences. This interactive Data Portal stands as a user-friendly interface to browse the most prominent lineages and Receptor Binding Domain (RBD) Spike mutations worldwide. The choice of RBD variants stems from the scientific evidence that immune response escape from vaccines and neutralizing antibodies mostly lies in this section of the SARS-CoV-2 genome.
The result of this work has been published on Journal of Translational Medicine (Massacci A. 2020)